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Side‐effects after inhalational anaesthesia for paediatric cerebral magnetic resonance imaging
Author(s) -
SANDNERKIESLING ANDREAS,
SCHWARZ GERHARD,
VICENZI MARTIN,
FALL ASTRID,
JAMES ROBERT L.,
EBNER FRANZ,
LIST WERNER F.
Publication year - 2002
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2002.00862.x
Subject(s) - medicine , sevoflurane , anesthesia , premedication , isoflurane , nausea , general anaesthesia , magnetic resonance imaging , halothane , incidence (geometry) , vomiting , surgery , radiology , physics , optics
Background: The aim of this study was to evaluate the type, incidence and duration of postprocedure side‐effects in 168 children within the first 72 h after inhalational anaesthesia for magnetic resonance imaging (MRI). Methods: Premedication and induction followed standardized routines. Maintenance of anaesthesia was performed with inhalational anaesthetics solely: isoflurane ( n =60 of 112; 53%), sevoflurane ( n =32 of 112; 29%), desflurane ( n =12 of 112; 11%) or halothane ( n = 8 of 112; 7%) using a strapped on face mask (FiO 2 =0.4; flow 5 l·min –1 ). When indicated, gadolinium was administered ( n =45; OF 112; 40%). Results: One hundred and twelve of 168 parents (67%) responded to questionnaires. In these 112 children, pathological MR findings were found supratentorially ( n =31; 28%), infratentorially ( n =9; 8%), extracerebrally ( n =12; 11%) or combined ( n =9; 8%). In 56 of these 112 children (50%), 14 different side‐effects were reported. One hour after anaesthesia, 55 children suffered between one and four side‐effects. Neurological side‐effects were associated with age ≥ 5 years ( P < 0.01) or infratentorial pathophysiology ( P < 0.01) and abdominal side‐effects ( P < 0.02), especially nausea ( P < 0.001) with age ≥ 5 years. Conclusions: Our findings indicate the need to inform parents of the incidence and variability of side‐effects after inhalational anaesthesia for minimally invasive, diagnostic procedures, such as MRI.