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Mexiletine Related Chronic Defibrillation Threshold Elevation: Case Report and Review of the Literature
Author(s) -
CRYSTAL EUGENE,
OVSYSHCHER I. ELI,
WAGSHAL ALAN B.,
KATZ AMOS,
ILIA REUVEN
Publication year - 2002
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1046/j.1460-9592.2002.00507.x
Subject(s) - mexiletine , medicine , defibrillation threshold , defibrillation , implantable cardioverter defibrillator , cardiology
CRYSTAL, E., et al. : Mexiletine Related Chronic Defibrillation Threshold Elevation: Case Report and Review of the Literature. Many antiarrhythmic drugs may produce a rise in defibrillation threshold. Mexiletine is a frequently used antiarrhythmic drug in patients with an implantable cardioverter defibrillator, usually thought of as producing no or minimal effects on the defibrillation threshold. The current case report presents a patient with an endocardial implantable cardioverter defibrillator being treated with mexiletine, which precluded the ability to defibrillate the patient.