Premium
Evaluation of a Single Stage Nitroglycerin Tilt Table Test for Diagnosis of Neurally Mediated Syncope
Author(s) -
ZENG CHUNYU,
LIU GUANGYAO,
YANG CHENGMING,
SUN WEI,
WANG YIELI,
HE DUOFEN
Publication year - 2001
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1046/j.1460-9592.2001.01494.x
Subject(s) - medicine , stage (stratigraphy) , tilt table test , anesthesia , cardiology , surgery , blood pressure , heart rate , paleontology , biology
ZENG, C., et al. : Evaluation of a Single Stage Nitroglycerin Tilt Table Test for Diagnosis of Neurally Mediated Syncope. The purpose of this study was to compare clinical outcomes between a single stage headup tilt table test (HUT) with infusion of 3.44 μg/kg per hour of nitroglycerin and a conventional multistage test with infusion of nitroglycerin from 1.72 μg/kg per hour to 5.16 μg/kg per hour in five successive stages. Thirty‐seven patients with recurrent syncope underwent both tests in a prospective, randomized, crossover fashion. During single stage HUT, a positive response occurred in 24 (64.9%) patients with unexplained syncope, an exaggerated response occurred in 3 (8.1%), a negative response in 7 (18.9%), and drug intolerance in 3 (8.1%). During the multistage HUT, these percentages were 62.2%, 16.2%, 13.5%, and 8.1%, respectively. Twenty healthy control subjects were involved in both tests. One of the control subjects had a positive response to single stage HUT, and two (10%) patients to multistage HUT. The duration of the test in single stage HUT was shorter than that in multistage HUT ( 8.6 ± 10.3 vs 38.6 ± 32.1 minutes, P < 0.01 ). The results showed that the single stage HUT was a fairly sensitive, specific, and a time‐efficient test for provoking neurally mediated syncope.