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How to prolong postoperative analgesia after caudal anaesthesia with ropivacaine in children: S‐ketamine versus clonidine
Author(s) -
De Negri Pasquale,
Ivani Giorgio,
Visconti Ciro,
De Vivo Paolo
Publication year - 2001
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2001.00742.x
Subject(s) - ropivacaine , medicine , clonidine , ketamine , anesthesia , sedation , surgery
Background : The aim of the study was to determine whether caudal S‐ketamine or clonidine prolonged analgesia together with ropivacaine. Methods : Sixty‐three boys, aged 1–5 years, who were undergoing minor surgery, were allocated in order to receive one of three solutions for caudal anaesthesia. Group R received 2 mg·kg –1 0.2% ropivacaine; group C, 2 mg·kg –1 0.2% ropivacaine + clonidine 2 μg·kg –1 ; and group K, 2 mg·kg –1 0.2% ropivacaine + S‐ketamine 0.5 mg·kg –1 . Results : Postoperative analgesia assessed by CHEOPS lasted 701 min in group K ( P < 0.05) compared with 492 min in group C and 291 min in group R. There were no significant differences between the groups for incidence of haemodynamic and respiratory alterations, motor block or sedation. Conclusions : This study demonstrates that S‐ketamine 0.5 mg·kg –1 when added to 0.2% caudal ropivacaine provides better postoperative analgesia than clonidine without any clinically significant side‐effect.