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Persistent mydriasis following intravenous atropine in a neonate
Author(s) -
Yung Michael,
Herrema Idse
Publication year - 2000
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2000.00561.x
Subject(s) - mydriasis , medicine , atropine , amitriptyline , anesthesia , parasympatholytic , antidepressant , muscarinic acetylcholine receptor , hippocampus , receptor
A neonate whose mother had recently taken amitriptyline developed fixed dilated pupils after a modest dose of intravenous atropine. Interaction of atropine with neonatal amitriptyline levels is suggested and evidence of neonatal effects from maternal antidepressant use is examined. There were no neurological sequelae, and the neonate’s pupils became reactive again after 7 h.