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Propofol and pain on induction: the effect of injectate temperature in children
Author(s) -
Pickford Alison,
Burden John,
Lewis Ian
Publication year - 2000
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2000.00461.x
Subject(s) - medicine , propofol , anesthesia , confidence interval , lidocaine , incidence (geometry) , randomized controlled trial , prospective cohort study , surgery , physics , optics
Summary A prospective, randomized, double‐blind study was conducted to determine whether cooled intravenous propofol reduces the incidence of pain on induction of anaesthesia in children. Seventy patients aged 3–10 years, ASA I or II, were randomized to receive 1% propofol plus 0.05% lidocaine either at room temperature (20–23°C) or cooled to 4C. Pain was assessed by a blinded observer using a behavioural scale. Data from 69 patients were analysed. The incidence of pain was 9/34 (26%, 95% confidence intervals 11–41%) in the room temperature injectate group and 5/35 (14%, 95% confidence intervals 3–26%) in the cold injectate group. These differences were not statistically significant ( P =0.21, chi‐squared test). Pain scores were similar in both groups.