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Remifentanil and propofol for sedation in children and young adolescents undergoing diagnostic flexible bronchoscopy
Author(s) -
ReyleHahn Matthias,
Niggemann Bodo,
Max Martin,
Streich Rita,
Rossaint Rolf
Publication year - 2000
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.2000.00440.x
Subject(s) - medicine , remifentanil , sedation , propofol , anesthesia , bronchoscopy , sedative , premedication , surgery
Summary Flexible fibreoptic bronchoscopy (FOB) has become a useful diagnostic and therapeutic procedure in children. We investigated 26 patients (3–14 years) for FOB using a new sedation strategy. All patients received oral premedication and inhalation of topical anaesthetic. Sedation for bronchoscopy was achieved with a continuous infusion of remifentanil and intermittent boluses of propofol. Propofol injection was repeated if sedation was inadequate. Sedation could be successfully performed in all children without adverse effects. Endtidal CO 2 concentration and arterial oxygen saturation remained stable throughout the study. All children were awake 5±1.3 min after stopping remifentanil infusion. Sedation with remifentanil/propofol is a new sedation strategy for diagnostic flexible paediatric bronchoscopy in children with spontaneous ventilation.