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Can a dose of 2μg??kg−1> caudal clonidine cause respiratory depression in neonates?
Author(s) -
BRESCHAN CHRISTIAN,
KRUMPHOLZ RUTH,
LIKAR RUDOLF,
KRASCHL RAIMUND,
SCHALK HANNES V.
Publication year - 1999
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.1999.t01-1-9120277.x
Subject(s) - clonidine , medicine , ropivacaine , anesthesia , depression (economics) , respiratory system , inhalation , surgery , economics , macroeconomics
Summary A case of multiple life‐threatening postoperative apnoeas in a term neonate undergoing inguinal herniorrhaphy and orchidopexy who received light inhalation anaesthesia combined with caudal block with 1 ml.kg‐1 ropivacaine 0.2% plus 2 μg??kg −1 clonidine is reported. The patient showed no apparent risk factors for postanaesthetic apnoea. Oxycardiorespirography five days after surgery only showed minor abnormalities. Clonidine though administered caudally in the usual dose of 2 μg??kg‐1 appeared to be the most likely cause for postanaesthetic apnoea in this neonate.