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Propofol‐nitrous oxide versus sevoflurane‐nitrous oxide for strabismus surgery in children
Author(s) -
Gürkan Yavuz,
Kiliçkan Levent,
Toker Kamíl
Publication year - 1999
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.1999.00399.x
Subject(s) - medicine , propofol , anesthesia , sevoflurane , oculocardiac reflex , strabismus , vomiting , strabismus surgery , nitrous oxide , postoperative nausea and vomiting , nausea , incidence (geometry) , surgery , reflex , physics , optics
Summary Vomiting is a common problem following strabismus surgery. We compared the effects of propofol‐N 2 O and sevoflurane‐N 2 O on the incidence of oculocardiac reflex and postoperative nausea and vomiting. Forty unpremedicated children, aged 3–15 years were randomly assigned to two groups of 20 patients. In group 1, anaesthesia was induced and maintained with propofol infusion(173 ± 41 μg·kg −1 ·min −1 ). In group 2, anaesthesia was induced with N 2 O (66%) in O 2 and incremental sevoflurane via face mask and maintained with sevoflurane. Both groups received 66% N 2 O in O 2 throughout surgery. The overall incidence of vomiting and antiemetic requirement in the first 24 h was significantly higher in sevoflurane‐N 2 O group than propofol‐N 2 O group ( P < 0.05). The propofol‐N 2 O group had significantly more episodes of oculocardiac reflex than sevoflurane‐N 2 O group ( P < 0.05). Propofol‐N 2 O anaesthesia results in a significantly lower incidence of postoperative vomiting, yet a significantly higher incidence of oculocardiac reflex.