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Anaesthesia and mitochondrial disease
Author(s) -
WALLACE J. J.,
PERNDT H.,
SKINNER M.
Publication year - 1998
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.1998.00725.x
Subject(s) - medicine , mitochondrial encephalomyopathies , mitochondrial disease , presentation (obstetrics) , disease , intensive care medicine , pathophysiology , mitochondrial myopathy , anesthesia , surgery , mitochondrial dna , pathology , biochemistry , chemistry , gene
Mitochondrial diseases, or encephalomyopathies, are an uncommon, heterogeneous group of disorders with variable clinical course and presentation. Many of these patients present for surgery, or undergo anaesthesia in the course of investigation of their illness. Unfortunately, little information exists on their management in anaesthetic texts and the literature. We report on the anaesthetic management of a paediatric patient with mitochondrial disease, and briefly discuss the pathophysiology and anaesthetic implications of these disorders.