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Retracted: Comparison of granisetron and droperidol in the prevention of vomiting after strabismus surgery or tonsillectomy in children
Author(s) -
FUJII YOSHITAKA,
SAITOH YUHJI,
TANAKA HIROYOSHI,
TOYOOKA HIDENORI
Publication year - 1998
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.1998.00206.x
Subject(s) - droperidol , medicine , granisetron , anesthesia , tonsillectomy , antiemetic , vomiting , strabismus surgery , adenoidectomy , strabismus , postoperative nausea and vomiting , surgery
This prospective, randomized, double‐blinded study evaluated the antiemetic efficacy of granisetron and droperidol in 80 ASA physical status I children, aged 4–10 years, undergoing strabismus surgery or tonsillectomy with or without adenoidectomy. After anaesthetic induction, the patients received either granisetron (40 μg·kg −1 , n =40) or droperidol (50 μg·kg −1 , n =40) intravenously. The incidence of vomiting during the first 24 h after anaesthesia was 15% and 38% after administering granisetron and droperidol, respectively(r)( P =0.02). The requirement for rescue antiemetic therapy for the treatment of two or more episodes of vomiting was 0% with granisetron and 18% with droperidol ( P =0.001). In conclusion, granisetron was superior to droperidol in reducing the incidence and frequency of postoperative vomiting in paediatric patients.