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Unexpected interaction of methylphenidate (Ritalin ® ) with anaesthetic agents
Author(s) -
RIRIE DOUGLAS,
RIRIE KIRSTEN,
SETHVIL,
FOX LIZANNE
Publication year - 1997
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.1997.d01-34.x
Subject(s) - methylphenidate , medicine , sedation , ketamine , anesthesia , nausea , vomiting , sedative , adverse effect , attention deficit disorder , pharmacology , psychiatry , attention deficit hyperactivity disorder
We report difficulty with conscious sedation of a child taking methylphenidate for attention deficit disorder and possible delayed adverse interaction of ketamine and methylphenidate resulting in severe nausea, vomiting and dehydration. The effects of methylphenidate and its potential interactions with anaesthetic agents is discussed. We suggest that anaesthesiologists who provide sedation or anaesthesia to patients receiving methylphenidate be aware of the potential need for high sedative doses and the possibility of undesirable interactions.