Premium
Haemodynamic responses to sevoflurane compared with halothane during inhalational induction in children[Note 1. Presented in part at the Annual Meeting of the ...]
Author(s) -
KERN C.,
ERB T.,
FREI F.J.
Publication year - 1997
Publication title -
pediatric anesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.704
H-Index - 82
eISSN - 1460-9592
pISSN - 1155-5645
DOI - 10.1046/j.1460-9592.1997.d01-124.x
Subject(s) - sevoflurane , halothane , medicine , anesthesia , hemodynamics , heart rate , blood pressure , inhalation
We studied the haemodynamic changes during induction of anaesthesia in 50 ASA I and II children (1–12 yrs) undergoing minor elective surgery. The patients were randomly divided into two groups to receive either halothane ( n =25) or sevoflurane ( n =25) in a mixture of O 2 and N 2 O (40:60) for mask induction of anaesthesia. Induction of anaesthesia was performed with an overpressure technique by administering rapid increases of gas concentrations, in increments of 1% up to 7% for sevoflurane and of 0.5% up to 3% for halothane. Induction was smooth and rapid in both groups but characterized by increases in heart rate and systolic blood pressure up to 20% especially in the sevoflurane group ( P <0.05); these increases in the latter group were significant compared with baseline and the halothane group ( P <0.05). No serious complications were observed. The authors conclude that more children experienced heart rate and blood pressure increases during the early stage of inhalational induction with sevoflurane compared with halothane.