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Simultaneous intracerebral EEG recordings of early auditory thalamic and cortical activity in human
Author(s) -
Yvert Blaise,
Fischer Catherine,
Guénot Marc,
KrolakSalmon Pierre,
Isnard Jean,
Pernier Jacques
Publication year - 2002
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1046/j.1460-9568.2002.02162.x
Subject(s) - electroencephalography , neuroscience , psychology , eeg fmri , audiology , medicine
We describe documented simultaneous intracerebral auditory evoked potentials from the auditory cortex and medial geniculate body (MGB) of a human patient. The MGB response lasted > 300 ms, with an initial negativity at 13.5 ms (N13), two positive peaks P21 and P29, and two broader negativities N50 and N200. P21 and N50 amplitudes were strongest for lowest tone frequencies, suggesting possible MGB tonotopic organization. Thalamic peaks were strongly interlaced with cortical activities recorded in Heschl's gyri before 30 ms: N13 preceded the first cortical component by 3.5 ms, then P21 and P29 preceded and lagged, respectively, the following two cortical polarity reversals by 1.5–2 ms. This study provides new functional data on the human MGB, and supports a more complex than simply relay‐like role of the thalamus in sound perception.