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Corticothalamic axons contact blood vessels as well as nerve cells in the thalamus
Author(s) -
Feig Sherry L.,
Guillery R. W.
Publication year - 2000
Publication title -
european journal of neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.346
H-Index - 206
eISSN - 1460-9568
pISSN - 0953-816X
DOI - 10.1046/j.1460-9568.2000.00093.x
Subject(s) - basement membrane , thalamus , anatomy , cats , electron micrographs , cytoplasm , biology , neurovascular bundle , axon , neuroscience , electron microscope , microbiology and biotechnology , medicine , physics , optics
Corticothalamic axons in cats and rats were studied after labelling by intracortical injections of axonally transported markers. Individual axons were traced to their terminal branches. Many preterminal segments had a tightly spiral or winding course which was often closely adjacent to a thalamic blood vessel. Electron micrographs of such axons showed them lying immediately adjacent to the vascular basement membrane, without the astrocytic cytoplasm that generally separates neural processes from the basement membrane of vessels. The functional nature of this neurovascular relationship remains to be explored.