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Temozolomide‐induced flare in high‐grade gliomas: a new clinical entity
Author(s) -
Rosenthal M. A.,
Ashley D. L.,
Cher L.
Publication year - 2002
Publication title -
internal medicine journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 70
eISSN - 1445-5994
pISSN - 1444-0903
DOI - 10.1046/j.1445-5994.2002.00242.x
Subject(s) - temozolomide , medicine , glioblastoma , chemotherapy , flare , glioma , oncology , cancer research , physics , astrophysics
A transient deterioration in neurological status following commencement of chemotherapy for high‐grade gliomas has not been previously described. We report eight cases of transient deterioration following administration of temozolomide, a relatively new cytotoxic agent used in the treatment of high‐grade gliomas. We believe this represents the novel clinical entity of temozolomide‐induced tumour flare. (Intern Med J 2002; 32: 346−348)