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Targeting molecular mechanisms in cancer
Author(s) -
Balleine Rosemary L.,
Kefford Richard F.
Publication year - 2002
Publication title -
anz journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 70
eISSN - 1445-2197
pISSN - 1445-1433
DOI - 10.1046/j.1445-2197.2002.02470.x
Subject(s) - medicine , cancer , disease , bioinformatics , computational biology , pathology , biology
Malignant disease is characterized by the disregulated growth of transformed cells. In recent years, dramatic insight into the molecular mechanisms of this phenomenon have come from basic cancer research. Detailed knowledge of the molecular pathology of cancer allows therapeutic agents to be designed that specifically target aberrant cellular processes. There are currently a number of targeted treatment strategies being evaluated. In the future, it is likely that this mechanistic approach will have a significant impact on clinical oncologyand the diagnostic evaluation of tumours.