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ACCURACY OF ENDOSCOPIC DIAGNOSIS OF HELICOBACTER PYLORI IN PATIENTS WITH HEMORRHAGIC PEPTIC ULCERS
Author(s) -
WONG REI MING,
OTA SHINICHI,
BAMBA HIROMI,
ITOYAMA SHINJI,
SEKINE SUSUMU,
KAWAMOTO CHIAKI,
YOSHIDA YUKIO
Publication year - 2003
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1046/j.1443-1661.2003.00211.x
Subject(s) - medicine , melena , helicobacter pylori , gastroenterology , rapid urease test , peptic , endoscopy , incidence (geometry) , peptic ulcer , complication , gastritis , physics , optics
Background: Recent progress in Helicobacter pylori eradication has resulted in dramatic improvements in the incidence of peptic ulcers and decreased rates of ulcer relapse. Because bleeding is an important complication of ulcer diseases, accurate diagnosis of H. pylori infection is necessary. Methods: We studied the efficacy of diagnostic methods to detect H. pylori in hemorrhagic peptic ulcer patients. A total of 59 patients who had received emergency endoscopy because of symptoms such as hematemesis, melena or tarry stool, were examined. Endoscopic methods of H. pylori diagnosis (culture, histological assessment and rapid urease test) and serum anti‐ H. pylori assays were used in the hemorrhagic peptic ulcer group and the control group. Results: The percentage of endoscopically determined H. pylori ‐negative patients was significantly higher in the hemorrhagic ulcer group than the control group ( P < 0.05). Out of the endoscopically determined H. pylori ‐negative patients in the hemorrhagic ulcer group, 78.9% were serologically H. pylori ‐positive. Conclusion: Endoscopic methods are not sufficient for the diagnosis of H. pylori infection in hemorrhagic ulcer patients. Therefore, serum anti‐ H. pylori assessment should also be performed for such patients.