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Acute Gastric Mucosal Injury Caused by Ingestion of Chlorinated Fungicide
Author(s) -
Kasamaki Shinji,
Kobayashi Shigeru,
Hayashida Yasuo,
Hirai Shu,
Ochiai Takumi,
Motoyama Hironobu,
Yokota Hiroo
Publication year - 2002
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1046/j.1443-1661.2002.00180.x
Subject(s) - medicine , lesion , infiltration (hvac) , biopsy , ingestion , gastric mucosa , pathology , stomach , stroma , edema , epithelium , gastroenterology , physics , immunohistochemistry , thermodynamics
We encountered a patient with acute gastric mucosal injury caused by ingestion of a chlorinated fungicide. Approximately 15 h after the episode of ingestion, endoscopic views were compatible with the acute gastric mucosal lesion of severe degree throughout the stomach. At that time, endoscopic biopsy showed congestion in the epithelial layer of the mucosa, along with lymphocytic infiltration that had likely existed from the onset of the condition. On the third day, the mucosal lesion looked more serious with peculiar hemorrhagic folds, and biopsy revealed exfoliation of the epithelial surface and neutrophilic infiltration in the stroma of the epithelial layer. On the seventh day, endoscopic images showed persistence of the lesion, but biopsy demonstrated the development of regenerating epithelium along with a marked reduction in infiltration of neutrophils and edema in the stroma.