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Superficial neuroendocrine carcinoma of the esophagus
Author(s) -
Iwamura Takeshi,
Shibata Naoya,
Termuhlen Paula,
Nagano Motoaki,
Yamada Hiromi,
Hatakeyama Kinta,
Hayashi Toru,
Toyoda Kiyokazu
Publication year - 2001
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1046/j.1443-1661.2001.00146.x
Subject(s) - medicine , chromogranin a , synaptophysin , carcinoembryonic antigen , enolase , esophagus , neuroendocrine carcinoma , carcinoma , pathology , immunohistochemistry , cancer
A 50‐year‐old man underwent subtotal esophagectomy for a superficial ulcerated tumor, 1.8 cm in length, located in the middle third of the esophagus. Histological examination of the resected specimen showed a stage I infiltrating neuroendocrine carcinoma. Tumor cells were immunohistochemically positive for chromogranin A, neuron‐specific enolase, synaptophysin, protein gene product 9.5 and carcinoembryonic antigen. Postoperative cisplatin‐based chemoradiation therapy was administered. Fourteen months after surgery, widely metastatic disease was noted and the patient died 3 months later.