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DETERMINING THE HORIZONTAL EXTENT OF EARLY GASTRIC CARCINOMA: TWO MODERN TECHNIQUES BASED ON DIFFERENCES IN THE MUCOSAL MICROVASCULAR ARCHITECTURE and DENSITY BETWEEN CARCINOMATOUS and NON‐CARCINOMATOUS MUCOSA
Author(s) -
Yao Kenshi,
Yao Tsuneyoshi,
Iwashita Akinori
Publication year - 2002
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1046/j.1443-1661.14.s1.16.x
Subject(s) - medicine , cancer , pathology , carcinoma , gastric mucosa , gastric carcinoma , stomach
Two modern endoscopic techniques are presented with a view to determining the horizontal extent of gastric cancer. They are based on differences in the microvascular structure and density of early gastric cancer compared with those of the non‐cancerous background mucosa. One technique requires magnifying endoscopy which can identify microvascular architecture that shows the characteristic findings of carcinoma. The other technique is an image‐processing technique which enhances the differences in microvascular structure and density between carcinomatous mucosa and non‐carcinomatous mucosa. We demonstrate an example of these techniques applied to an intramucosal carcinoma of a differentiated type, the margin of which could not be determined simply by traditional endoscopy with dye spreading. Magnified observation could detect a demarcation line between the carcinoma and non‐carcinomatous mucosa. In addition, the image‐processing technique enhanced the contrast of redness between cancerous area and non‐cancerous mucosa. Both of these techniques are useful for detecting the precise extent of a carcinoma. The combined application of these techniques should be helpful in determining the precise horizontal extent of early gastric cancer.