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Current Australian practice in the prevention and management of corneal allograft rejection
Author(s) -
Barker Nigel H,
Henderson Timothy RM,
Ross Carolyn A,
Coster Douglas J,
Williams Keryn A
Publication year - 2000
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1046/j.1442-9071.2000.00335.x
Subject(s) - medicine , immunosuppression , keratitis , prednisolone , corneal transplant , graft rejection , corneal transplantation , surgery , dermatology , immunology , transplantation
Purpose : To determine current practices in the prevention and management of corneal allograft rejection in Australia. Methods : A questionnaire was circulated to attendees at the 1998 Eye Bank Meeting in Adelaide. Twenty‐four responses were received and analysed. Results : All respondents used topical corticosteroids for routine prophylaxis and to treat established rejection episodes. Prednisolone acetate was the most frequently prescribed topical corticosteroid. Systemic non‐steroidal immunosuppression was prescribed almost exclusively for high‐risk grafts. Seventy‐five per cent of surgeons used systemic antiviral agents for the treatment of graft rejection in patients with Herpes simplex keratitis. Conclusion : There was a wide variation amongst surgeons in the choice of therapy for routine prophylactic immunosuppression as well as for the treatment of established corneal allograft rejection.