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Reduced‐intensity stem cell transplantation in two cases of metastatic renal cell carcinoma
Author(s) -
AOYAMA YASUTAKA,
NAKAMAE HIROHISA,
YAMAMURA RYOUSUKE,
MAKITA KAORI,
SHIMA ETSUKO,
OHTA KENSUKE,
TAKUBO TAKAYUKI,
YAMANE TAKAHISA,
SUGIMURA KAZUNOBU,
KAWASHIMA HIDEKNORI,
NAKATANI TATSUYA,
HINO MASAYUKI
Publication year - 2003
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1046/j.1442-2042.2003.00700.x
Subject(s) - medicine , transplantation , renal cell carcinoma , hematopoietic stem cell transplantation , disease , stem cell , carcinoma , leukemia , oncology , pathology , biology , genetics
Allogeneic hematopoietic stem‐cell transplantation can induce curative graft‐versus‐leukemia reactions in patients with hematological malignancies. There is also evidence of such an effect in patients with solid tumors. We report two patients with metastatic renal cell carcinoma who underwent RIST. In both patients, disease progression was observed 6 months after transplantation. However, one patient had transient symptoms of tumor progression after the occurrence of acute graft‐versus‐host disease, consistent with graft‐versus‐tumor effects.