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Elevated serum estradiol suggesting recurrence of Leydig cell tumor nine years after radical orchiectomy
Author(s) -
Maeda Toshihiro,
Itoh Naoki,
Kobayashi Ko,
Takahashi Atsushi,
Masumori Naoya,
Tsukamoto Taiji
Publication year - 2002
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1046/j.1442-2042.2002.00538.x
Subject(s) - medicine , retroperitoneal lymph node dissection , leydig cell tumor , leydig cell , orchiectomy , lymph node , metastasis , dissection (medical) , lymph node metastasis , urology , oncology , testicular cancer , radiology , cancer , hormone , luteinizing hormone
We report a case of a Leydig cell tumor that showed retroperitoneal lymph node metastasis 9 years after radical orchiectomy. Elevated serum estradiol (E2) suggested recurrence of the Leydig cell tumor. Retroperitoneal lymph node dissection (RPLND) was performed and the lymph node was proved histopathologically to have a metastatic Leydig cell tumor. After RPLND, serum E2 returned to the normal range. This is the first reported case in which changes in the endocrinological findings were useful as likely tumor markers to detect the recurrence of a Leydig cell tumor.