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Adult‐onset idiopathic hypogonadotropic hypogonadism presented with erectile and ejaculatory disorder
Author(s) -
KOBAYASHI TAKASHI,
OKUNO HIROSHI,
NISHIYAMA HIROYUKI,
NAKAMURA EIJIRO,
OGAWA OSAMU,
KAWAHARA MASAHIRO,
SHIMATSU AKIRA
Publication year - 2002
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1046/j.1442-2042.2002.00522.x
Subject(s) - hypogonadotropic hypogonadism , medicine , hypothalamic disease , erectile dysfunction , testosterone (patch) , luteinizing hormone , endocrinology , ejaculation , magnetic resonance imaging , gonadotropin releasing hormone , hormone , radiology
A 37‐year‐old man who had fathered a child five years previously presented with erectile and ejaculatory disorder. Endocrinological examinations revealed isolated luteinizing hormone‐releasing hormone (LHRH) deficiency of hypothalamus, resulting in hypogonadotropic hypogonadism, and no causative abnormality was detected in imaging studies, including magnetic resonance imaging (MRI). Having a diagnosis of adult‐onset hypogonadotropic hypogonadism, the patient received pulsatile subcutaneous administration of gonadotropin‐releasing hormone (GnRH). Sperm analysis and serum level of testosterone improved to normal in a few months. His wife became pregnant using artificial insemination with her husband's semen 15 months after the beginning of the treatment.