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Renal transplantation with aged donors
Author(s) -
Nakatani Tatsuya,
Kim Taku,
Takemoto Yoshiaki,
Kishimoto Taketoshi
Publication year - 2001
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1046/j.1442-2042.2001.00338.x
Subject(s) - medicine , cadaveric spasm , transplantation , creatinine , surgery , renal function , kidney transplantation , kidney , urology
Research indicates that aged heart‐beating cadaveric donors cause greater risk factors in kidney transplantation. The influence of age on the outcome of non‐heart‐beating (NHB) cadaveric renal transplantations has not yet been clarified. From July 1986 to May 1999, 63 patients who received cadaveric renal transplantation at Osaka City University Hospital and Osaka City General Hospital were divided into two groups according to their age. Renal function and graft‐survival rates of the two groups were compared. The mean values of nadir donor serum creatinine were significantly worse ( P < 0.05) in the aged donor group. In the aged donor group the percentage of immediately functioning grafts was lower and the percentage of non‐functioning grafts was higher. During the first 10 years post‐transplant, graft survival in the aged donor group was significantly lower than that in the younger donor group. We conclude that cadaveric renal transplantation from NHB aged donors can be to the detriment of renal function and graft survival rates compared to transplantation from younger donors.