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Androgen deprivation in combination with radical prostatectomy for localized prostate cancer
Author(s) -
Naito Seiji
Publication year - 2001
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1046/j.1442-2042.2001.00329.x
Subject(s) - medicine , prostatectomy , prostate cancer , androgen deprivation therapy , urology , metastasis , prostate , localized disease , adjuvant , oncology , cancer
Radical prostatectomy is the only potential modality for cure in patients with localized prostate cancer. However, the lack of reliable and accurate clinical staging frequently leads to incomplete excision of tumor, with the consequences of early local recurrence or distant metastasis. Thus, the role of neoadjuvant or adjuvant hormonal treatment has been investigated in improving disease‐free or cause‐specific survival. This review reports the current status and problems of such androgen deprivation in combination with radical prostatectomy for localized prostate cancer.