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Conservative treatment of childhood phimosis with topical conjugated equine estrogen ointment
Author(s) -
Yanagisawa Naoko,
Baba Katsuyuki,
Yamagoe Masanari,
Iwamoto Teruaki
Publication year - 2000
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1046/j.1442-2042.2000.00127.x
Subject(s) - medicine , foreskin , estrogen , gynecomastia , surgery , genetics , biology , cell culture
AbstractPurpose: To assess the application of topical conjugated equine estrogen for the treatment of boys with phimosis.Methods: Fifteen boys with phimosis were included in the study. Conjugated equine estrogen (Premarin®) 0.1% ointment was applied on the prepuce once daily. The treatment was continued until the prepuce was fully retractable. The patient was examined each second week up to a maximum treatment of 8 weeks. Retractability and the appearance of the foreskin were graded before and after treatment.Results: Thirteen of 15 boys (87%) referred with phimosis were successfully treated with conjugated equine estrogen ointment. An adverse effect of gynecomastia was seen in one boy (7%). Conclusion : Conjugated equine estrogen ointment application for phimosis may be an alternative to surgery.