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Investigation of the relationship between low Apgar scores and early neonatal thyroid function
Author(s) -
Sak Erbil,
Akin Mehmet,
Aktürk Zekeriya,
Akin Fulya,
Atay Enver,
Aydoğdu Cavit,
Yüzkollar Erdoğan
Publication year - 2000
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1046/j.1442-200x.2000.01275.x
Subject(s) - medicine , cord blood , thyroid function , thyroxine binding globulin , thyroid , thyroid stimulating hormone , obstetrics , apgar score , hormone , thyroid function tests , vaginal delivery , cord , endocrinology , pediatrics , fetus , thyroid hormones , pregnancy , surgery , biology , genetics
Background : The aim of the present study was to assess the effects of low Apgar scores on perinatal thyroid function.Methods: Forty full‐term infants delivered by the normal spontaneous vaginal route were enrolled into the study. All babies had 1 and 5 min Apgar scores below 4. The control group consisted of 26 full‐term healthy neonates. Cord blood and serum tri‐iodothyronine (T 3 ), thyroxine (T 4 ), reverse tri‐iodothyronine (rT 3 ), free thyroxine (FT 4 ), thyroid‐stimulating hormone (TSH) and thyroid‐binding globulin (TBG) determinations were performed by an enzyme immunoassay method.Results: The mean values of FT 4 and T 4 observed in the cord blood of the study group were significantly lower compared with matched controls, whereas the mean TSH values were significantly higher. There were no differences in concentrations of T 3 , rT 3 and TBG between the two groups.Conclusions: These results demonstrate the existence of transient hypothyroidism at birth in babies with Apgar scores below 4 delivered by the spontaneous vaginal route.