Premium
Clinical experiences in Sakai City Hospital during the massive outbreak of enterohemorrhagic Escherichia coli O157 infections in Sakai City, 1996
Author(s) -
Fukushima Hisao,
Hashizume Takao,
Morita Yoshiki,
Tanaka Junko,
Azuma Katsumi,
Mizumoto Yuki,
Kaneno Masako,
MatsuUra MotoO,
Kitani Kazushi Konma And Teruo
Publication year - 1999
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1046/j.1442-200x.1999.4121041.x
Subject(s) - outbreak , medicine , escherichia coli , antibiotics , pediatrics , microbiology and biotechnology , virology , biology , biochemistry , gene
In the middle of July 1996, a massive outbreak of hemorrhagic colitis (HC) occurred among elementary schoolchildren in Sakai city. This is the most widespread outbreak of O157 infection ever experienced to our knowledge. Lunch foods supplied in the elementary schools in Sakai were contaminated by Escherichia coli ( E. coli ) O157. One hundred and twenty‐one cases developed hemolytic uremic syndrome (HUS) from 12 680 symptomatic patients, including putative secondary infections, and three girls died during this outbreak. Sakai City Hospital is one of the core medical facilities in this community; hence, 425 children with HC were treated at the hospital. Antibiotics were used extensively on all patients. Among them, 12 children developed HUS. All 425 children, including the patients with HUS, recovered without significant sequelae. In the present paper, the clinical experiences during this massive outbreak of E. coli O157 infection in Sakai City Hospital are described.