Premium
Absence of BAT‐26 instability in gastric intestinal metaplasia
Author(s) -
Jin Zhe,
Tamura Gen,
Satoh Michiko,
Meguro Toru,
Miura Takayuki,
Hayashi Masahiro,
Osakabe Mitsumasa,
Ohmura Kiyonari,
Ogata Shinya,
Endoh Yasushi,
Motoyama Teiichi
Publication year - 2001
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.2001.01220.x
Subject(s) - microsatellite instability , intestinal metaplasia , pathology , gastric mucosa , cancer , metaplasia , biology , gastroenterology , stomach , medicine , microsatellite , genetics , gene , allele
BAT‐26 instability, a sensitive marker for the high‐frequency microsatellite instability (MSI‐H) phenotype, was analyzed in samples of gastric cancer and in adjacent intestinal metaplastic mucosae. Although all MSI‐H gastric cancer samples showed BAT‐26 instability, as assessed using 12 dinucleotide microsatellite markers, BAT‐26 instability was not found in the adjacent intestinal metaplastic mucosa in any of the samples.