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Endomyometriosis arising in the uterosacral ligament: A case report including a literature review and immunohistochemical analysis
Author(s) -
Matsuzaki Sachiko,
Murakami Takashi,
Sato Shinji,
Moriya Takuya,
Sasano Hironobu,
Yajima Akira
Publication year - 2000
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.2000.01061.x
Subject(s) - immunohistochemistry , uterosacral ligament , stromal cell , pathology , immunostaining , stroma , epithelium , anatomy , progesterone receptor , estrogen receptor , smooth muscle , biology , medicine , vagina , cancer , breast cancer
We report a case of endomyometriosis arising in the left uterosacral ligament of a 29‐year‐old woman. The central cavity of the uterine‐like mass was lined by pseudo‐stratified columnar epithelium and endometrial stroma. The wall of the cyst consisted of bundles of smooth muscle cells. Immunohistochemical analysis demonstrated both α ‐estrogen receptor and progesterone receptor immunoreactivities in the epithelial, stromal and smooth muscle cells. A relatively high proliferating activity was also demonstrated in these cells by Ki‐67 immunostaining. These findings suggest that the mass was hormone dependent and had a relatively rapid evolution.