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Anaplastic carcinoma of the pancreas with rhabdoid features
Author(s) -
Kuroda Naoto,
Sawada Taeko,
Miyazaki Eriko,
Hayashi Yoshihiro,
Toi Makoto,
Naruse Keishi,
Fukui Takayuki,
Nakayama Hirofumi,
Hiroi Makoto,
Taguchi Hirokuni,
Enzan Hideaki
Publication year - 2000
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.2000.00996.x
Subject(s) - pathology , pancreas , anaplastic carcinoma , eosinophilic , nucleolus , differential diagnosis , carcinoma , biology , medicine , cytoplasm , biochemistry
The malignant rhabdoid tumor (MRT) is histologically characterized by the invasive proliferation of polygonal to ovoid cells with abundant eosinophilic cytoplasm and eccentric vesicular nuclei with a prominent nucleolus. MRT frequently occurs in the kidney, but may also arise in other organs. However, MRT should be strictly distinguished from carcinomas with rhabdoid features. A post‐mortem examination of a 68‐year‐old woman found an anaplastic carcinoma of the pancreas with rhabdoid features displaying extensive invasion into the neighboring tissues. To the best of our knowledge, this is the first case of a pancreatic tumor with rhabdoid features. Pathologists should consider that carcinomas showing rhabdoid features may also appear in the pancreas. As pancreatic tumors with rhabdoid features have characteristic histopathological features and poor prognosis compared to other pancreatic tumors, careful histopathological differential diagnosis is important.