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So‐called ‘hybrid’ lesion of desmoplastic and conventional ameloblastoma: Report of a case and review of the literature
Author(s) -
Takata Takashi,
Miyauchi Mutsumi,
Ogawa Ikuko,
Zhao Ming,
Kudo Yasusei,
Sato Sunao,
Takekoshi Toshitsugu,
Nikai Hiromasa,
Tanimoto Keiji
Publication year - 1999
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.1999.00972.x
Subject(s) - ameloblastoma , lesion , pathology , medicine , curettage , mandible (arthropod mouthpart) , adamantinoma , odontogenic tumor , anatomy , maxilla , biology , botany , genus
So‐called ‘hybrid’ lesion of ameloblastoma, which is composed of desmoplastic ameloblastoma and conventional follicular/plexiform ameloblastoma, is an unusual variant of ameloblastoma and only eight cases of ‘hybrid’ lesion have been published in the English literature. To enhance knowledge of this interesting tumor, we add a case of ‘hybrid’ lesion that occurred in the right mandible of a 48‐year‐old Japanese male. Radiographic examination disclosed a honeycomb appearance at the anterior alveolar region, combined with a unicystic radiolucency in the molar region of the mandibular body. Histologically, the former showed microscopic features of desmoplastic ameloblastoma and the latter those of follicular ameloblastoma with focal granular cell transformation. The lesion was enucleated with curettage of surrounding bone and the lesional cavity was marsupialized. Although tumor tissues reappeared at 3, 5, 7 and 14 months after the surgery, the patient has remained disease free for 11 years after the last vaporization by CO 2 laser of the recurred tumor. Many more cases of ‘hybrid’ lesion are needed to clarify the clinicopathological, histopathological and biological characteristics of this interesting variant of ameloblastoma.