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A case of anaplastic large cell (Ki‐1) lymphoma of B‐cell phenotype, occurring in Waldenström’s macroglobulinemia
Author(s) -
Hamada Tomomi,
Ishizuka Hikari,
Asai Yasukiyo,
Yamazaki Tetsuo,
Sawada Umihiko,
Hasegawa Hiromasa,
Uchida Toshikazu
Publication year - 1999
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.1999.00958.x
Subject(s) - macroglobulinemia , waldenstrom macroglobulinemia , lymphoplasmacytic lymphoma , lymphoma , anaplastic large cell lymphoma , pathology , bone marrow , medicine , cd30 , immunostaining , large cell lymphoma , large cell , immunohistochemistry , immunology , cancer , adenocarcinoma , multiple myeloma
A case of anaplastic large cell (Ki‐1) lymphoma of B‐cell lineage occurred in a 59‐year‐old male with Waldenström’s macroglobulinemia. Immunostaining of the lymphoma cells showed sporadic positivity for IgM and occasional positivity for κ chain. This immunoglobulin specificity is the same as that of plasmacytoid lymphocytes in the bone marrow; therefore anaplastic transformation of Waldenström’s macroglobulinemia was strongly suggested. This seems to be the first reported case of anaplastic large cell lymphoma, confirmed by CD30 expression, arising in Waldenström’s macroglobulinemia.