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Application of tyramide signal amplification system to immunohistochemistry: A potent method to localize antigens that are not detectable by ordinary method
Author(s) -
Toda Yoshinobu,
Kono Katsuhiko,
Abiru Hitoshi,
Kokuryo Kumiko,
Endo Mareyuki,
Yaegashi Hiroshi,
Fukumoto Manabu
Publication year - 1999
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.1999.00875.x
Subject(s) - immunohistochemistry , antigen , pathology , biology , medicine , immunology
Tyramide signal amplification–avidin–biotin complex (TSA‐ABC) method is a powerful technique used to detect antigens that are not detectable by ordinary immunohistochemistry. It is worth trying in cases where localization of antigens by the conventional method has failed and antibodies are precious.