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Pseudovascular squamous cell carcinoma of the uterine cervix: A lesion that may simulate an angiosarcoma
Author(s) -
Horie Yasushi,
Kato Masako
Publication year - 1999
Publication title -
pathology international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.73
H-Index - 74
eISSN - 1440-1827
pISSN - 1320-5463
DOI - 10.1046/j.1440-1827.1999.00841.x
Subject(s) - angiosarcoma , pathology , basal cell , uterine cervix , cervix , medicine , lesion , carcinoma , cancer
A case of pseudovascular squamous cell carcinoma in the uterine cervix of a 64‐year‐old woman was examined. Histologically, the lesion consisted of atypical, large, non‐keratinizing squamous cells that exhibited not only acantholytic changes but also pseudovascular changes. Immunohistochemically, these tumor cells were positive for cytokeratin, epithelial membrane antigen and carcinoembryonic antigen, but none of them were positive for Factor VIII‐related antigen or CD34. To our knowledge, pseudovascular carcinoma of the uterine cervix has not been described in the literature. Pathologists should be aware of this unusual form of cervical squamous cell carcinoma, particularly in the differential diagnosis of angiosarcoma.