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Vertical ophthalmoplegia in a demented patient with striatopallidodentate calcification
Author(s) -
Watanabe Yasuhiro,
Shimizu Yasutaka,
Urakami Katsuya,
Matsushima Eiji,
Nakashima Kenji
Publication year - 2003
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1046/j.1440-1819.2003.01145.x
Subject(s) - pseudobulbar palsy , progressive supranuclear palsy , parkinsonism , globus pallidus , dystonia , medicine , dementia , calcification , psychology , pathology , basal ganglia , disease , psychiatry , central nervous system
A case is presented here of a 73‐year‐old man who showed signs of dementia, supranuclear vertical ophthalmoplegia, pseudobulbar palsy, axial dystonia, mild rigidity, and parkinsonian gait. Computed tomography of the head revealed symmetrical calcification in the striatum, globus pallidus and dentate nucleus to an extraordinary degree. No metabolic conditions were observed that could explain the intracranial calcification. Oral administration of levodopa improved the patient's motor symptoms to some extent. Ophthalmoplegia, parkinsonism and dementia combined are typically seen in patients with progressive supranuclear palsy. However, the present case and a few others that have been reported would seem to indicate that these unique symptoms might also be found in patients with intracranial calcification.