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A comparison of middle latency auditory‐evoked response in obstructive sleep apnea syndrome before and after treatment
Author(s) -
Miyamoto Tomoyuki,
Miyamoto Masayuki,
Takekawa Hidehiro,
Kubo Jin,
Hirata Koichi,
Katayama Soichi
Publication year - 2001
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1046/j.1440-1819.2001.00846.x
Subject(s) - vigilance (psychology) , obstructive sleep apnea , polysomnography , epworth sleepiness scale , anesthesia , medicine , audiology , apnea , arousal , scalp , psychology , surgery , neuroscience
The ascending reticular activating system seems to be affected by nocturnal hypoxia in obstructive sleep apnea syndrome (OSAS) patients so that their vigilance level is decreased. To evaluate the change in vigilance level in OSAS patients, polysomnography, the Epworth Sleepiness Scale and middle latency auditory‐evoked responses (MLR) were measured before and after treatment in seven men with OSAS (mean age 45.4 ± 12.9 years, mean body mass index 33.3 ± 7.6 kg/m 2 ). After treatment there was significant improvement of nocturnal hypoxia in OSAS. Peak amplitude of P1 in MLR increased after treatment. There was also improvement of the electrical field distribution of MLR on the scalp. The results suggest that the decreased vigilance level in OSAS patients is reversible with treatment.