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Narcolepsy and other non‐SAS hypersomnia in sleep breathing disorders clinic
Author(s) -
Banno Katsuhisa,
Shiomi Toshiaki,
Sasanabe Ryujiro,
Hasegawa Rika,
Otake Kazuo,
Yamakawa Hiroki,
Kobayashi Tadashi,
Horiba Kiyoshi,
Nishino Seiji
Publication year - 2001
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1046/j.1440-1819.2001.00826.x
Subject(s) - narcolepsy , cataplexy , medicine , sleep apnea , sleep disorder , anesthesia , multiple sleep latency test , obstructive sleep apnea , psychology , pediatrics , psychiatry , excessive daytime sleepiness , modafinil , insomnia
Four of the 708 snorers (0.56%), referred to our sleep breathing disorders clinic for the past 2 years were diagnosed as having narcolepsy‐cataplexy. Detecting HLA DRB1*1501/DQB1*0602 positive was informative for differentiating genuine narcolepsy from non‐sleep apnea syndrome (non‐SAS) hypersomnia in our clinic. A non‐SAS obese boy, diagnosed as having essential hypersomnia syndrome, was found to be HLA DRB1*1502/DQB1*0601 positive. His hypocretin concentration was 206 pg/mL in the cerebrospinal fluid.