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Relationship between hypersomnia and respiratory disorder during sleep in Prader–Willi syndrome
Author(s) -
Hiroe Yu,
Inoue Yuichi,
Higami Shigeru,
Suto Yuji,
Kawahara Ryuzo
Publication year - 2000
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1046/j.1440-1819.2000.00697.x
Subject(s) - sleep (system call) , psychology , respiratory system , psychiatry , medicine , pediatrics , computer science , operating system
To assess whether hypersomnia in Prader–Willi syndrome (PWS) patients is related to the respiratory disorder during sleep (RDDS), we made a systematic evaluation regarding the relationship between the two disorders in three patients. All patients showed hypersomnia manifested as the long duration of night sleep and shortened sleep latencies of multiple sleep latency test. Although magnetic resonance imaging and laboratory studies revealed obstruction of the upper airway and mild increase of esophageal pressure during sleep, the number of other apneic episodes or awakenings was not as frequent. From the above results, we speculate that the mechanism of excessive daytime sleepiness in PWS is not caused by RDDS and quite resembles that of essential hypersomnia.

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