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Relative power contributions of unit discharges simultaneously recorded in the mesencephalic reticular formation
Author(s) -
Kodama Tohru,
Honda Yoshiko,
Nakao Mitsuyuki,
Sato Seisho,
Yamamoto Mitsuaki
Publication year - 2000
Publication title -
psychiatry and clinical neurosciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.609
H-Index - 74
eISSN - 1440-1819
pISSN - 1323-1316
DOI - 10.1046/j.1440-1819.2000.00671.x
Subject(s) - disinhibition , serotonin , neuroscience , reticular formation , 5 ht receptor , sleep (system call) , psychology , midbrain , medicine , central nervous system , receptor , computer science , operating system
In order to investigate mutual interactions between neuronal discharges in the mesencepahlic reticular formation, relative power contributions (RPC) were estimated during sleep–wake cycles and serotonin (5HT)‐depleted conditions by the administration of parachlorophenylalanine (PCPA). The RPC for most of the neurons dominated in the lower frequency range below 0.4 Hz during rapid eye movement (REM) sleep and the PCPA‐treated conditions, which were qualitatively reproduced by the neural network model under global disinhibition. The results supported the hypothesis that the peculiar dynamics of neuronal activities during REM sleep, 1/f fluctuations, were generated by neuronal interactions augmented by the release from the global inhibition of 5HT.