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Screening for intracranial aneurysms in autosomal dominant polycystic kidney disease
Author(s) -
HUGHES Peter DV,
BECKER Gavin J
Publication year - 2003
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1046/j.1440-1797.2003.00161.x
Subject(s) - medicine , autosomal dominant polycystic kidney disease , asymptomatic , subarachnoid haemorrhage , aneurysm , disease , subarachnoid hemorrhage , polycystic kidney disease , polycystic kidney , kidney disease , surgery , radiology
SUMMARY: Screening patients with autosomal dominant polycystic kidney disease (ADPKD) for asymptomatic intracranial aneurysms has been proposed as a method of reducing the morbidity and mortality associated with aneurysm rupture. However, recent studies have shown lower spontaneous rupture rates of small aneurysms and higher risks of significant complications with interventions than previously reported. Risk‐benefit analysis has not demonstrated any benefit of screening ADPKD patients without a history of subarachnoid haemorrhage (SAH) for intracranial aneurysms, and has suggested that screening might cause harm.