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Natural logarithmic formula: Not an alternative method for estimating Kt/V in paediatric haemodialysis
Author(s) -
Jiravuttipong Apichat,
Jones Colin L
Publication year - 2000
Publication title -
nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 61
eISSN - 1440-1797
pISSN - 1320-5358
DOI - 10.1046/j.1440-1797.2000.00016.x
Subject(s) - medicine , etiology , surgery , natural history , conservative treatment
SUMMARY Many methods have been used to measure urea kinetic modelling (UKM) in haemodialysis patients. Formal UKM has been recommended as the best method to calculate Kt/V in adult and paediatric patients. The natural logarithmic formula for Kt/V was established as the best alternative for adult patients but there is no data comparing the two methods of determining UKM in children and adolescents. We compared Kt/V derived from formal UKM with that derived from the natural logarithmic formula in seven patients having 74 episodes of treatment with haemodialysis. The patients' ages ranged from 7 to 16 years. The mean percent difference between the two methods was 11.4 ± 9.0% and the total percent error was 29.3%. When compared for different means of vascular access, the mean percent difference between the two methods for arteriovenous (AV) vascular access ranged from 3.7% in a 7 year old to 9.6% in a 10 year old, and the mean percent difference in the venovenous (VV) vascular access subgroup ranged from 16.5% in a 7 year old to 25.5% in a 10 year old. These results show that the natural logarithmic formula consistently overestimates Kt/V in both AV and VV vascular access, suggesting it may not be adequate for a paediatric haemodialysis population.