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Primary squamous cell carcinoma of the brain. A rare autopsy case
Author(s) -
Shirabe Teruo,
Fukuoka Keiko,
Watanabe Akira,
Imamura Kazuhiro,
Ishii Ryoji
Publication year - 2003
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1046/j.1440-1789.2003.00499.x
Subject(s) - pons , medulla oblongata , medicine , pathology , autopsy , brainstem , dysphagia , spinal cord , anatomy , central nervous system , radiology , psychiatry
In the present study, a rare autopsy case of primary squamous cell carcinoma of the brain is described. The patient was a 49‐year‐old man who showed brainstem symptoms and signs. These included oculomotor, abducens and facial palsies, dysphagia, dysarthria, and long tract signs such as quadriplegia with Babinski's signs during the 3‐year and 6‐month course of his illness. Neuropathologically, poorly differentiated squamous cell carcinoma was seen in the pons, medulla oblongata, part of the midbrain and spinal cord, the base of the cerebellum, the hypothalamus, the optic chiasm, and the left parahippocampal gyrus. The base of the pons and medulla oblongata were extensively destroyed by tumor cells. The relevant literature regarding primary squamous cell carcinomas of the brain was reviewed, and the characteristic features of this rare condition were discussed.