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Introduction: Pick's disease and frontotemporal dementia
Author(s) -
Amano Naoji,
Iseki Eizo
Publication year - 1999
Publication title -
neuropathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 61
eISSN - 1440-1789
pISSN - 0919-6544
DOI - 10.1046/j.1440-1789.1999.00258.x
Subject(s) - frontotemporal dementia , neuropathology , parkinsonism , dementia , disease , pick's disease , frontal lobe , psychology , neuroscience , medicine , pathology
There is no universally accepted morphological definition of Pick's disease. The concept of frontotemporal dementia (FTD) was proposed by the Lund‐Manchester Group in 1994 and comprises three main subtypes: frontal lobe degeneration type, Pick type and motor neuron disease type. Subsequently, familial or hereditary FTD has been identified, and ‘FTD and parkinsonism linked to chromosome 17’ was defined in 1996. However, there are still unresolved aspects of the neuropathology of FTD. This paper describes the origin and development of the concept of FTD with special reference to the neuropathological problems.