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Evaluation of standardized versus individualized total parenteral nutrition regime for neonates less than 33 weeks gestation
Author(s) -
Yeung MY,
Smyth JP,
Maheshwari R,
Shah S
Publication year - 2003
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1046/j.1440-1754.2003.00246.x
Subject(s) - medicine , gestation , parenteral nutrition , pediatrics , intensive care medicine , pregnancy , genetics , biology
Objective: To evaluate the difference in nutrient intakes and biochemical responses in newborn infants <33 weeks gestation who received standardized versus individualized total parenteral nutrition (TPN) regimes. Method: Comparison of nutrient intakes and daily biochemical responses in newborn infants <33 weeks gestation who received standardized regime versus those who received individualized TPN regimes from day 2 to day 7 of life. Results: Twenty‐seven infants in the standardized TPN group and 31 infants in the individualized TPN group were compared. There were no statistically significant differences ( P > 0.05) between the two groups in gestation, birthweight, Clinical Risk Index for Babies scores, daily TPN volume intake and biochemical responses. Infants in the standardized TPN group received less sodium ( P < 0.01) and no potassium on day 2 as required, more protein ( P < 0.02) every day, and more calcium and phosphate ( P < 0.02 from day 4). Conclusion: There were no significant clinical and statistical differences in biochemical responses in newborn infants <33 weeks gestation who received standardized versus individualized TPN regimes during the first week of life. The economic cost of TPN provision using standardized TPN formulation was approximately 30% lower.