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Intracranial venous thrombosis and pulmonary embolism with antiphospholipid syndrome in systemic lupus erythematosus
Author(s) -
Yuen SF,
Lau KF,
Steinberg AW,
GrattanSmith PJ,
Hodson EM
Publication year - 2001
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1046/j.1440-1754.2001.00673.x
Subject(s) - medicine , pulmonary embolism , antiphospholipid syndrome , venous thrombosis , cerebral venous sinus thrombosis , thrombosis , lupus anticoagulant , lupus erythematosus , antibody , immunology
Abstract : The presence of antiphospholipid antibodies is associated with arterial and venous thrombosis. A 14‐year‐old girl, with systemic lupus erythematosus (SLE), developed headache and cough and was found to have intracranial venous sinus thrombosis with secondary pulmonary embolism associated with antiphospholipid syndrome. Clinical and radiological improvement occurred with anticoagulation therapy. Because SLE is commonly associated with antiphospholipid antibodies, thromboembolic events should be considered in the differential diagnosis of both cough and headache in children with SLE.