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Regional differences in outcome for very low‐birthweight infants: Do they persist at 7–8 years of age?
Author(s) -
Darlow Ba,
Horwood Lj,
Mogridge N
Publication year - 2000
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1046/j.1440-1754.2000.00553.x
Subject(s) - medicine , pediatrics , confounding , cohort , low birth weight , cohort study , wechsler preschool and primary scale of intelligence , gestational age , wechsler adult intelligence scale , wechsler intelligence scale for children , pregnancy , psychiatry , cognition , pathology , biology , genetics
Objective : To determine whether regional differences in early neonatal morbidity in a national cohort of very low‐birthweight (VLBW) infants persisted at 7–8 years of age. Methods : Perinatal data collected prospectively from birth on all VLBW infants born in New Zealand in 1986 and admitted to a neonatal unit included the hospital principally caring for the infant: hospitals A–D being level III hospitals and ‘Other’ including the smallest level III and all level II hospitals. At 7–8 years of age, 298 surviving children (96% survivors living in New Zealand) were assessed at a home visit. Parents were given a comprehensive questionnaire to complete, the children underwent a visual examination and were tested with the Revised Wechsler Intelligence Scale for Children and the child’s teacher was sent a questionnaire to complete. Results : Neonatal survival was significantly greater in the two largest hospitals (A and B) and this difference in survival remained at 7–8 years of age after adjustment for perinatal factors ( P < 0.05). There were no differences between hospitals in risks of long‐term sensorineural disability and behavioural or educational outcomes. There were interhospital differences in rates of visual problems and, after adjustment for confounding factors, there remained a marginally significant ( P = 0.06) increased risk of myopia in hospital D. Conclusions : Despite differences in early morbidity favouring larger hospitals, there were no substantive differences in long‐term (7–8 years) outcomes across a range of measures in this national cohort of VLBW infants.