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A randomized controlled trial of two methods for collection of sterile urine in neonates
Author(s) -
TOBIANSKY R,
EVANS N
Publication year - 1998
Publication title -
journal of paediatrics and child health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.631
H-Index - 76
eISSN - 1440-1754
pISSN - 1034-4810
DOI - 10.1046/j.1440-1754.1998.00272.x
Subject(s) - medicine , urine , randomized controlled trial , gestation , catheter , birth weight , surgery , urinary catheterization , pregnancy , genetics , biology
Objective: To test whether urethral catheterization (UC) is better than suprapubic bladder aspiration (SPA) as a method for collection of sterile urine in neonates. Methods: Thirty‐three babies, requiring sterile collection of urine, were randomly assigned to either urethral catheterization ( n =16), median gestation 28±3.9 weeks, median birth weight 968 g (range 650–4100) or SPA ( n =17), median gestation 26±5.6 weeks, median birth weight 926 g (range 771–4070). The primary outcome was success in obtaining urine. Secondary outcomes were complications and urine culture results. Results: Some urine was obtained in 11 (64.7%) babies in the SPA group and in 13 (81.2%) babies in the catheter group. Sufficient urine for analysis (>0.5 ml) was obtained in 10 (58.8%) in the SPA group versus 5 (31.2%) babies in the catheter group. There were more contaminated specimens in the catheter group but this was not significant in this small study. Conclusions: In this small randomized controlled trial urethral catheterization offered no significant advantage over SPA.